• Machine-learning-derived heart and brain age are independently associated with cognition 

      Iakunchykova, Olena; Schirmer, Henrik; Vangberg, Torgil Riise; Wang, Yunpeng; Benavente, Ernest D.; van Es, René; van de Leur, Rutger R.; Lindekleiv, Haakon; Attia, Zachi I.; Lopez-Jimenez, Francisco; Leon, David A.; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-31)
      Background and purpose - A heart age biomarker has been developed using deep neural networks applied to electrocardiograms. Whether this biomarker is associated with cognitive function was investigated.<p> <p>Methods - Using 12-lead electrocardiograms, heart age was estimated for a population-based sample (N = 7779, age 40–85 years, 45.3% men). Associations between heart delta age (HDA) and ...